Changing the paradigm for AMD
Until now, therapies for Age-Related Macular Degeneration (AMD) have only focused on late stage treatments that attempt to manage the symptoms experienced by patients — by which stage vision loss, and or damage has already occurred.
Currently, the sole option for the more aggressive wet form of AMD is the administration of expensive and invasive anti-VEGF injections. These are only suitable for advanced or end stage disease, and merely address complications associated with AMD.
In contrast, 2RT® Retinal Rejuvenation Therapy enables ophthalmologists the potential to intervene earlier in the disease process with the aim of slowing the degeneration process.
Taking the heat out of photocoagulation
For Diabetic Macular Edema and Proliferative Retinopathy, CW retinal photocoagulation remains a mainstream pathway. The use of CW photocoagulation to treat retinal disease represents a two-fold challenge. First — the treatment causes irreversible collateral damage to retinal tissue, and, second — it is an often painful procedure for the patient.
Clinical studies have shown 2RT® can deliver a therapeutic benefit for the treatment of Clinically Significant Macular Edema (CSME) similar to that achieved through thermal retinal photocoagulation laser treatment, but without the collateral damage associated with the conventional method. Using 500 times less energy than retinal photocoagulation, 2RT® eliminates the incidence of heat damage to the retina and surrounding cells.1
Gentle stimulation, natural renewal
Retinal Rejuvenation Therapy stimulates a biological healing process that results in cellular rejuvenation, renewing the entire transport mechanism of the retina and improving the hydraulic conductivity of Bruch’s Membrane. In suitable patients, this rejuvenation process preserves or improves functional vision and reduces disease progression.
Ellex 2RT® utilizes an ultra-short nanosecond laser pulse that allows the precise and specific delivery of laser energy to nano-sized targets within the cellular structure of ageing RPE cells – without causing collateral damage to the overlying photoreceptor rods and cones of the retina.
“… if we can slow down the basal rate of Bruch’s Membrane aging with 2RT® and restore function to what it was when the patient was in their teens, we should be able to significantly delay AMD onset.”
1. Casson RJ. Et al., “Pilot randomized trial of a nanopulse retinal laser versus conventional photocoagulation for the treatment of diabetic macular oedema”, Clin Experiment Ophthalmol. 2012 Aug;40(6):604-10